The heart of the argument is a take-down of the late 19th-century idea that Buddhist karma is like evolution, and the late 20th-century idea that Buddhist meditation is about stress-reduction. In fact, Buddhism seeks to lead people to extinction and its meditation traditions are about "stress induction" - making us see the world as a prison, a nightmare, to be escaped at all costs. (Lopez is rather Theravada-focused in this part of the discussion...) What drives evolution, Lopez suggests, is precisely what Buddhist practice tries to wean us from!
Far better, Lopez concludes, to let Buddhism be what it is, instead of reducing it to a mere confirmation of something else. If the past has a future, it is in its description of an alternative world, one that calls into question so many of the fundamental assumptions of our scientific world. (123)